Partial Sequence of L1 Gene in HPV 16 and HPV 18 Isolated from Head-Neck Squamous Cell Carcinoma Tissues in Bangladesh

S M Rashed Ul Islam, Md. Sayeam Khandaker, Bishnu Pada Dey, Syed Farhan Ali Razib, Kabir Hossen, Joy Prokash Debnath, Shamim Ahmed, Afzalun Nessa
October 2026
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Abstract

Human papillomavirus is one of the most crucial determinants responsible for the progression of head-neck squamous cell carcinoma (HNSCC). Here, we report partial L1 gene sequences of two high-risk etiological agents, HPV-16 and HPV-18, extracted through biopsies from multiple head-neck tissue regions of HNSCC patients in Bangladesh. HPV DNA was detected in 24.8% of HNSCC-confirmed samples, with HPV-16 being the most prevalent strain. The consensus sequences were submitted to GenBank under accession numbers PV107410.1, PV113111.1, PV113112.1, PV113113.1, PV113114.1, PV113115.1, PV126527.1, PV126528.1, PV126529.1, PV126530.1, PV126531.1, PV126532.1, and PV357593.1.

Type
Journal article
Publication
Microbiology Resource Announcements, American Society for Microbiology (ASM), 15(10), e00298-26. PMID: 42734331
Joy Prokash Debnath
Joy Prokash Debnath
Graduate Research Assistant

I study the regulatory programs that drive cell behavior in cancer and the brain, pairing machine learning with experimental validation.

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