First Report of Partial HPV 16 and HPV 18 L1 Gene Sequences from Head-Neck Squamous Cell Carcinoma Tissues in Bangladesh

S M Rashed Ul Islam, Md. Sayeam Khandaker, Bishnu Pada Dey, Syed Farhan Ali Razib, Kabir Hossen, Joy Prokash Debnath, Shamim Ahmed, Anwara Nessa
August 2026
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Abstract

Human papillomavirus is one of the most crucial determinants responsible for the progression of head-neck squamous cell carcinoma (HNSCC). Here, we report partial L1 gene sequences of two high-risk etiological agents, HPV-16 and HPV-18, extracted through biopsies from multiple head-neck tissue regions of HNSCC patients in Bangladesh. HPV DNA was detected in 24.8% of HNSCC-confirmed samples, with HPV-16 being the most prevalent strain. The consensus sequences were submitted to GenBank under accession numbers PV107410.1, PV113111.1, PV113112.1, PV113113.1, PV113114.1, PV113115.1, PV126527.1, PV126528.1, PV126529.1, PV126530.1, PV126531.1, PV126532.1, and PV357593.1.

Type
Journal article
Publication
Accepted at Microbiology Resource Announcements, American Society for Microbiology (ASM)
Joy Prokash Debnath
Joy Prokash Debnath
Graduate Research Assistant

My research interests include computational biology and machine learning.

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